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CAS No. : [1206123-37-6]
Synonyms : APD334
IUPAC Name : (R)-2-(7-((4-Cyclopentyl-3-(trifluoromethyl)benzyl)oxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C26H26F3NO3 | Mol. Weight : 457.49 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Etrasimod is a potent, selective, and orally bioavailable antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor, exhibiting an IC50 value of 1.88 nM in CHO cells. It is being developed as a next-generation therapeutic agent for the treatment of multiple sclerosis (MS) and other autoimmune disorders.
References : Buzard D. J. et al.: ACS Med Chem Lett., 5(12), 1313-1317, 2014.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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