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Etrumadenant

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SI-7001

Etrumadenant, >98% (HPLC)

CAS No. : [2239273-34-6]

Synonyms : AB-928

IUPAC Name : 3-(2-Amino-6-(1-((6-(2-hydroxypropan-2-yl)pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)pyrimidin-4-yl)-2-methylbenzonitrile

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Chemical Properites
Mol. Formula :
C23H22N8O
Mol. Weight :
426.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Etrumadenant functions as a potent, orally active dual A2A/A2B receptor antagonist. Through inhibition of adenosine‑mediated immune suppression, it enhances antitumor immunity and displays clear immunomodulatory and antitumor effects across multiple tumor models.

References : Seitz L. et al.: Invest. New Drugs, 37(4), 711-721, 2019; Daniel DiRenzo et al.: Cancer Immunol. Res., 7 (2), A162, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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