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Evacetrapib

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SI-6776

Evacetrapib, >98% (HPLC)

CAS No. : [1186486-62-3]

Synonyms : LY-2484595

IUPAC Name : (1S,4r)-4-(((S)-5-((3,5-Bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazol-5-yl)amino)-7,9-dimethyl-2,3,4,5-tetrahydro-1H-benzo[b]azepin-1-yl)methyl)cyclohexane-1-carboxylic acid

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Chemical Properites
Mol. Formula :
C31H36F6N6O2
Mol. Weight :
638.66
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Evacetrapib selectively inhibits CETP with nanomolar potency, blocking recombinant human CETP (IC50= 5.5 nM) and plasma CETP activity (IC50 = 36 nM). It is a valuable tool for studying CETP‑mediated HDL and LDL regulation.

References : Cao. G. et al.: J. Lipid Res., 52(12), 2169-76, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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