Evobrutinib

SI-5469

Evobrutinib, >98% (HPLC)

CAS No. : [1415823-73-2]

MDL No. : MFCD30502975

Synonyms : M-2951

IUPAC Name : 1-(4-(((6-Amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)piperidin-1-yl)prop-2-en-1-one

Applications : Evobrutinib is a highly selective BTK inhibitor with an IC50 of 37.9 nM. It has potential antineoplastic activity.

References : Crawford J. J. et al.: J. Med Chem., 61(6), 2227-2245, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.