Exarafenib

SI-7546

Exarafenib, >98% (HPLC)

CAS No. : [2639957-39-2]

Synonyms : RAF/KIN-2787

IUPAC Name : (S)-N-(3-(2-(((R)-1-Hydroxypropan-2-yl)amino)-6-morpholinopyridin-4-yl)-4-methylphenyl)-3-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Exarafenib selectively targets RAF kinases with oral activity and shows efficacy in cancers driven by RAF dependency, including diverse BRAF mutation classes. It inhibits MAPK signaling in melanoma cell lines and displays strong antitumor activity.

References : Miller N. et al.: J. Clin. Oncol., 40(16), e15099, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.