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Exemestane diol impurity

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Exemestane diol impurity, >98%

CAS No. : [1204325-02-9]

IUPAC Name : (8R,9S,10R,13S,14S,17R)-17-Hydroxy-17-((R)-1-hydroxyethyl)-10,13-dimethyl-6-methylene-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

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Chemical Properites
Mol. Formula :
C22H30O3
Mol. Weight :
342.48
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Exemestane, which is a potent, irreversible oral steroidal aromatase inhibitor. Exemestane is used in hormone-dependent breast cancer research.

References : Di Salle E. et al.: J.Steroid Biochem Mol Biol., 49(4-6), 289-94, 1994; Miki Y. et al.: Bone 10(17), 5717-23, 2004; Goss P.E. et al.: Clin Cancer Res., 10(17), 5717-23, 2004; Zaccheo T. D. et al.: J.Steroid Biochem Mol Biol., 44(4-6), 677-80, 1993.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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