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Ezetimibe tetrahydropyran analog

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Ezetimibe tetrahydropyran analog, >98%

CAS No. : [1296129-15-1]

IUPAC Name : (2R,3R,6S)-N,6-Bis(4-fluorophenyl)-2-(4-hydroxyphenyl)tetrahydro-2H-pyran-3-carboxamide

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H21F2NO3
Mol. Weight :
409.43
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Ezetimibe, which is a potent, selective, cholesterol absorption inhibitor, used to lower cholesterol.

References : Clader J. W. et al.: J. Med Chem., 47(1), 1, 2004; During A. et al.: J. Nutr, 135(10), 2305, 2005; Davis H. R Jr. et al.: Arterioscler Thromb Vasc Biol, 21(12), 2032, 2001; Delaney W. E. et al.: Antimicrob Agents Chemother, 50(7), 2471, 2006; van Heek M. et al.: Br. J. Pharmacol., 134(2), 409, 2001; Davis H. R. et al.: J. Atheroscler Thromb., 14(3), 99, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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