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Fadraciclib

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SI-7122

Fadraciclib, >98% (HPLC)

CAS No. : [1070790-89-4]

Synonyms : CYC-065

IUPAC Name : (2R,3S)-3-((6-(((4,6-Dimethylpyridin-3-yl)methyl)amino)-9-isopropyl-9H-purin-2-yl)amino)pentan-2-ol

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Chemical Properites
Mol. Formula :
C21H31N7O
Mol. Weight :
397.53
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fadraciclib is a second‑generation, orally available ATP‑competitive inhibitor of CDK2 and CDK9 with IC50 values of 5 nM and 26 nM, respectively.

References :
Cocco E. et al.: Br. J. Cancer., 115(3), 303-11, 2016. Sumana D. et al.: 15(2), S14-S15, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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