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Fadrozole hydrochloride

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SI-5404

Fadrozole hydrochloride, >98% (HPLC)

CAS No. : [102676-31-3]

MDL No. : MFCD00866239

Synonyms : rac-FAD286 hydrochloride; rac-LCI 699 hydrochloride; CGS 16949A hydrochloride

IUPAC Name : 4-(5,6,7,8-Tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride

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Chemical Properites
Mol. Formula :
C14H13N3 . HCl
Mol. Weight :
259.74
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fadrozole hydrochloride is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM. Fadrozole hydrochloride can be used for the treatment of breast cancer.

References : Browne L. J. et al.: J. Med Chem., 34(2), 725-36, 1991; Gunson D. E. et al.: Br. J. Cancer., 72(1), 72-75, 1995; Morales-Montor J. et al.: Int. J. Parasitol. 32(11), 1379-1387, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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