Fedratinib-d9

SL-9450

Fedratinib-d₉, >98%

Related CAS No. : [936091-26-8] of the free base compound

IUPAC Name : 3-((5-Methyl-2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-4-yl)amino)-N-(2-(methyl-d₃)propan-2-yl-1,1,1,3,3,3-d₆)benzenesulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is a deuterium labelled version of Fedratinib, which is a potent and selective ATP-competitive JAK2 inhibitor, exhibiting IC₅₀ values of 3 nM for both JAK2 and JAK2V617F kinases. It demonstrates 35-fold and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces apoptosis in cancer cells and holds significant potential in research focused on myeloproliferative disorders.

References : Wernig G. et al.: Cancer Cell 13(4), 311-20, 2008; Geron I. et al.: Cancer Cell 13(4), 321-30, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.