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Felodipine-d6 EP impurity B

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SL-5916

Felodipine-d6 EP impurity B, >98%

CAS No. : [1794786-23-4]

Synonyms : Felodipine dimethyl ester-d6

IUPAC Name : Bis(methyl-d3) 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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Chemical Properites
Mol. Formula :
C17H11D6Cl2NO4
Mol. Weight :
376.26
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version an impurity of Felodipine (Felodipine-d6 EP impurity B), which is a long-acting 1,4-dihydropyridine calcium channel blocker, used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

References : Johnson J. D. et al.: J. Pharmacol Exp Ther., 226(2), 330-334, 1983; Rodler S. et al.: J. Mol Cell Cardiol., 27(10), 2295-2302, 1995; Yiu S. et al.: J. Med Chem., 39(23), 4576-4582, 1996; Ding Y. et al.: Hypertension 32(4), 718-723, 1998; Yang Z. et al.: Cardiovasc Res., 53(1), 227-231, 2002; Perez-Reyes E. et al.: J. Pharmacol Exp Ther., 328(2), 621-627, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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