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Fexagratinib

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SI-6721

Fexagratinib, >98% (HPLC)

CAS No. : [1035270-39-3]

Synonyms : AZD-4547; ADSK-091

IUPAC Name : N-(5-(3,5-Dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3R,5S)-3,5-dimethylpiperazin-1-yl)benzamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C26H33N5O3
Mol. Weight :
463.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fexagratinib is a selective FGFR inhibitor with low‑nanomolar potency against FGFR1–3 and reduced activity toward FGFR4 (IC50 = 165 nM). It serves as a valuable tool for probing FGFR‑dependent tumor biology.

References : Gavine P. R. et al.: Cancer Res., 72(8), 2045-2056, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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