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Fexaramine

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SI-7102

Fexaramine, >98% (HPLC)

CAS No. : [574013-66-4]

IUPAC Name : Methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate

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Chemical Properites
Mol. Formula :
C32H36N2O3
Mol. Weight :
496.65
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fexaramine is a potent, selective FXR agonist (EC50 = 25 nM) with no activity across a broad panel of nuclear receptors.

References : Lam I. P. et al.: Am J. Physiol. Gastrointest. Liver Physiol., 297(1), G90-7, 2009; Downes M. et al.: Mol. Cell., 11(4),1079-92, 2003; Fang S. et al.: Nat. Med., 21(2), 159-65, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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