Fexaramine

SI-7906

Fexaramine, >98% (HPLC)

CAS No. : [574013-66-4]

IUPAC Name : Methyl (E)-3-(3-(N-((4'-(dimethylamino)-[1,1'-biphenyl]-4-yl)methyl)cyclohexanecarboxamido)phenyl)acrylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Fexaramine activates FXR with low‑nanomolar potency (EC₅₀ = 25 nM) and displays no cross‑reactivity with major nuclear receptors such as RXRα, PPARα/γ/δ, PXR, LXRα, TRβ, RARβ, CAR, ERRγ, or VDR. Its clean selectivity profile makes it a valuable tool for probing FXR‑dependent metabolic and bile‑acid signaling pathways.

References : Lam I. P. et al.: Am. J. Physiol Gastrointest Liver Physiol., 297(1), G90-7, 2009; Downes M. et al.: Mol Cell, 11(4), 1079-92, 2003; Fang S. et al.: Nat Med., 21(2), 159-65, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.