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Fexofenadine cyclopropyl ester impurity

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Fexofenadine cyclopropyl ester impurity, >98%

CAS No. : [880088-78-8]

Synonyms : 4-(Cyclopropylcarbonyl)-α,α-dimethylbenzeneacetic acid methyl ester

IUPAC Name : Methyl 2-(4-(cyclopropanecarbonyl)phenyl)-2-methylpropanoate

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Chemical Properites
Mol. Formula :
C15H18O3
Mol. Weight :
246.31
Appearance :
Brown liquid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fexofenadine, which is a histamine H1 receptor antagonist, used in seasonal allergic rhinitis and chronic idiopathic urticarial.

References : Corcostegui R. et al.: Drugs R D, 6(6), 371-38, 2005; Petri N. et al.: Pharm Res., 21(8), 1398-1404, 2004; Liu T. et al.: Heart Rhythm., 3(8), 948-956, 2006; Kamath A. V. et al.: J. Pharm Sci., 94(2), 233-239, 2005; Tahara H. et al.: Drug Metab Dispos., 33(7), 963-968, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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