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Fexofenadine EP impurity A

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SL-6500

Fexofenadine EP impurity A, >98%

CAS No. : [76811-98-8]

MDL No. : MFCD08063764

Synonyms : Fexofenadine USP related compound A; Fexofenadinone

IUPAC Name : 2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid

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Chemical Properites
Mol. Formula :
C32H37NO4
Mol. Weight :
499.65
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fexofenadine (Fexofenadine EP impurity A), which is a histamine H1 receptor antagonist, used in seasonal allergic rhinitis and chronic idiopathic urticarial.

References : Corcostegui R. et al.: Drugs R D, 6(6), 371-38, 2005; Petri N. et al.: Pharm Res., 21(8), 1398-1404, 2004; Liu T. et al.: Heart Rhythm., 3(8), 948-956, 2006; Kamath A. V. et al.: J. Pharm Sci., 94(2), 233-239, 2005; Tahara H. et al.: Drug Metab Dispos., 33(7), 963-968, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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