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FIIN-3

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SI-7272

FIIN-3, >98% (HPLC)

CAS No. : [1637735-84-2]

IUPAC Name : N-(4-((3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-(6-((4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)ureido)methyl)phenyl)acrylamide

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Chemical Properites
Mol. Formula :
C34H36Cl2N8O4
Mol. Weight :
691.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : FIIN‑3 irreversibly inhibits FGFR1–4 with IC50 values ranging from 13.1 to 35.3 nM, enabling durable suppression of FGFR signaling pathways. It is widely used in studies of FGFR‑dependent tumor biology.

References : Tan L . et al.: Proc. Natl. Acad. Sci. U S A., 111(45), E4869-77, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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