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Fimepinostat

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SL-1642

Fimepinostat, >98%

CAS No. : [1339928-25-4]

MDL No. : MFCD22420823

Synonyms : CUDC-907

IUPAC Name : N-Hydroxy-2-(((2-(6-methoxypyridin-3-yl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)(methyl)amino)pyrimidine-5-carboxamide

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Chemical Properites
Mol. Formula :
C23H24N8O4S
Mol. Weight :
508.55
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fimepinostat potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes with IC50 of 1.7/5.0/1.8/2.8 nM and 19/54/39 nM for HDAC1/2/3/10 and PI3Kα/β/δ, respectively.

References : Qian C. et al.: Clin. Cancer Res., 18(15), 4104-4113, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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