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Finasteride amido 2-(2-methylpropanoic acid)

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SL-6393

Finasteride amido 2-(2-methylpropanoic acid), >98%

CAS No. : [116285-37-1]

Synonyms : 2-Methyl-N-[[(5a,17b)-3-oxo-4-azaandrost-1-en-17-yl]carbonyl]alanine

IUPAC Name : 2-((4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-Dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamido)-2-methylpropanoic acid

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Chemical Properites
Mol. Formula :
C23H34N2O4
Mol. Weight :
402.54
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Finasteride in human bile (metabolite), which is a potent, reversible inhibitor of the rat type 1 5 alpha-reductase, used in the treatment of benign prostatic hyperplasia (BPH) and male pattern baldness (MPB).

References : Azzolina B. et al.: J. Steroid Biochem Mol Biol., 61(1-2), 55-64, 1997; Bologna M. et al.: Urology 45(2), 282-290, 1995; Wang L. G. et al.: Cancer Res., 57(4), 714-719, 1997; Clark R. L. et al.: Teratology 42(1), 91-100, 1990; Rittmaster R. S. et al.; Endocrinology 136(2), 741-748, 1995.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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