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Finerenone related impurity

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Finerenone related impurity, >98%

CAS No. : [2389020-00-0]

IUPAC Name : Benzyl 4-(4-cyano-2-methoxyphenyl)-2,8-dimethyl-5-oxo-1,4,5,6-tetrahydro-1,6-naphthyridine-3-carboxylate

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Chemical Properites
Mol. Formula :
C26H23N3O4
Mol. Weight :
441.49
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Finerenone, which is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist. Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold). Finerenone has the potential for cardiorenal diseases research, such as type 2 diabetes mellitus and chronic kidney disease.

References : Bärfacker L. et al.: ChemMedChem., 7(8), 1385-1403, 2012; González-Blázquez R. et al.: Front Pharmacol., 9, 1131, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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