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Fingolimod EP impurity B

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Fingolimod EP impurity B, >98%

CAS No. : [745767-97-9]

IUPAC Name : 2-Amino-2-(4-heptylphenethyl)propane-1,3-diol

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Chemical Properites
Mol. Formula :
C18H31NO2
Mol. Weight :
293.44
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fingolimod (Fingolimod EP impurity B), which is a sphingosine 1-phosphate (S1P) antagonist and immunomodulating agent for the treatment of multiple sclerosis.

References : Rolin J. et al.: Cancer Immunol Immunother. 59(4), 575-586, 2010; Szepanowski F. et al.: J. Neuroinflammation 13(1), 143, 2016; Airas L. et al.: J. Nucl. Med., 56(2), 305-310, 2015; Shirakabe K. et al.: J Gastroenterol Hepatol., Jan 15, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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