Fingolimod impurity F

SL-9479

Fingolimod impurity F, >98%

CAS No. : [2741267-35-4]

IUPAC Name : 1-Ethyl 3-methyl 2-acetamido-2-(4-octylphenethyl)malonate

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Applications : This is an impurity of Fingolimod, which is a sphingosine 1-phosphate (S1P) antagonist and an immunomodulating agent for the treatment of multiple sclerosis.

References : Rolin J. et al.: Cancer Immunol Immunother. 59(4), 575-586, 2010; Szepanowski F. et al.: J. Neuroinflammation 13(1), 143, 2016; Airas L. et al.: J. Nucl. Med., 56(2), 305-310, 2015; Shirakabe K. et al.: J. Gastroenterol Hepatol., Jan 15, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.