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Fipaxalparant

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SI-6856

Fipaxalparant, >98% (HPLC)

CAS No. : [1195941-38-8]

Synonyms : SAR-100842

IUPAC Name : 2-(4-Methoxy-3-(3-methylphenethoxy)benzamido)-2,3-dihydro-1H-indene-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C27H27NO5
Mol. Weight :
445.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fipaxalparant selectively inhibits the LPA₁ receptor with nanomolar potency (IC50= 31 nM, β‑arrestin assay) and is orally active. It is a valuable tool for probing LPA₁‑driven signaling in inflammation and fibrosis.

References : Ellery J. et al.: Eur J Pharmacol., 833, 8-15, 2018; Kihara Y. et al.: Exp. Cell Res., 333(2), 171-7, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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