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Firmonertinib

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SI-7959

Firmonertinib, >98% (HPLC)

CAS No. : [1869057-83-9]

Synonyms : Alflutinib; Furmonertinib; AST-2818

IUPAC Name : N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C28H31F3N8O2
Mol. Weight :
568.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Firmonertinib is a brain‑penetrant, orally active EGFR inhibitor that selectively targets activating mutations and the T790M resistance mutation. Its pharmacological profile supports research applications in advanced NSCLC, particularly models driven by EGFR exon 20 insertions.

References : Shi Y. et al.: Journal of Thoracic Oncology, Volume 12, Issue 11, Supplement 2S2138, 2017; Spira I. A. et al.: Journal of Clinical Oncology, 42(16), TPS8668, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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