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CAS No. : [2130958-55-1]
Synonyms : Alflutinib mesylate; Furmonertinib mesylate; AST-2818 mesylate
IUPAC Name : N-(2-((2-(Dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C28H31F3N8O2 • CH3SO2OH | Mol. Weight : 664.71 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Firmonertinib mesylate is an orally active, brain‑penetrant EGFR inhibitor that selectively targets activating mutations and the T790M resistance mutation. Its pharmacological profile supports research applications in advanced NSCLC, including models driven by EGFR exon 20 insertions.
References : Shi Y. et al.: Journal of Thoracic Oncology, Volume 12, Issue 11, Supplement 2S2138, 2017; Spira I. A. et al.: Journal of Clinical Oncology, 42(16), TPS8668, 2024.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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