Firsocostat (S)-enantiomer

SI-6084

Firsocostat (S)-enantiomer, >98% (HPLC)

CAS No. : [2128714-16-7]

Synonyms : NDI-010976 (S)-enantiomer; ND-630 (S)-enantiomer; GS-0976 (S)-enantiomer

IUPAC Name : (S)-2-(1-(2-(2-Methoxyphenyl)-2-((tetrahydro-2H-pyran-4-yl)oxy)ethyl)-5-methyl-6-(oxazol-2-yl)-2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidin-3(2H)-yl)-2-methylpropanoic acid

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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : The (S)‑enantiomer of Firsocostat is the less active stereoisomer of this dual ACC1/ACC2 inhibitor. It is commonly used to assess the impact of stereochemistry on ACC binding and metabolic pathway modulation.

References : Harriman G. et al.: Proc. Natl. Acad. Sci., U S A, 113(13), E1796-805, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.