Flavopiridol

SI-7763

Flavopiridol, >98% (HPLC)

CAS No. : [146426-40-6]

Synonyms : Alvocidib; L86-8275; HMR-1275

IUPAC Name : 2-(2-Chlorophenyl)-5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Flavopiridol inhibits CDK1, CDK2, and CDK4 with IC₅₀ values of 30–170 nM in a competitive manner, reflecting its broad‑spectrum CDK‑targeting profile. It is commonly employed to study CDK‑dependent cell‑cycle control and transcriptional regulation.

References : De Azevedo W. F. Jr. et al.: Proc. Natl. Acad. Sci. U S A., 93(7), 2735-40, 1996; Carlson B. A. et al.: Cancer Res., 56(13), 2973-8, 1996; Senderowicz A. M. et al.: Invest New Drugs., 17(3), 313-20, 1999; Kim K. S. et al.: J. Med. Chem., 43(22), 4126-34, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.