Flavopiridol

SI-7859

Flavopiridol, >98% (HPLC)

CAS No. : [146426-40-6]

Synonyms : Alvocidib; L86-8275; HMR-1275

IUPAC Name : 2-(2-Chlorophenyl)-8-((4S,5S)-3,5-dihydroxy-1-methylpiperidin-4-yl)-5,7-dihydroxy-4H-chromen-4-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Flavopiridol is a competitive inhibitor of multiple CDKs, displaying potent activity against CDK1 (IC₅₀ = 30 nM), CDK2 (IC₅₀ = 170 nM), and CDK4 (IC₅₀ = 100 nM). Its broad CDK‑inhibitory profile makes it a valuable tool for investigating CDK‑dependent cell‑cycle progression.

References : Mahoney E. et al.: Blood, 120(6), 1262-1273, 2012; Keskin H. et al.: Cell Div, 7, 11, 2012; Kim K. S. et al.: J. Med. Chem., 43(22), 4126-34, 2000; Jianliang X. u. et al.: Cell Commun Signal., 17(1), 85, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.