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CAS No. : [131740-09-5]
Synonyms : Alvocidib hydrochloride; L86-8275 hydrochloride; HMR-1275 hydrochloride
IUPAC Name : 2-(2-Chlorophenyl)-5,7-dihydroxy-8-((3R,4S)-3-hydroxy-1-methylpiperidin-4-yl)-4H-chromen-4-one hydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H20ClNO5 • HCl | Mol. Weight : 438.3 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Flavopiridol hydrochloride competitively inhibits CDK1, CDK2, and CDK4 with IC50 values of 30–170 nM, reflecting its broad CDK‑targeting profile. It is commonly employed to study CDK‑dependent mechanisms governing cell‑cycle regulation and transcription.
References : Mahoney E. et al.: Blood, 120(6), 1262-127, 2012; Keskin H. et al.: Cell Div., 7:11. 2012; Kim K. S. et al.: J. Med. Chem., 43(22), 4126-34, 2000.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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