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Flecainide acetate

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SL-6438

Flecainide acetate, >98%

CAS No. : [54143-56-5]

MDL No. : MFCD00214290

Synonyms : R-818

IUPAC Name : N-(Piperidin-2-ylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide

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Chemical Properites
Mol. Formula :
C17H20F6N2O3 . CH3CO2H
Mol. Weight :
474.40
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Flecainide acetate is a class 1C antiarrhythmic drug, especially used for the management of supraventricular arrhythmia; works by blocking the Nav1.5 sodium channel in the heart, causing prolongation of the cardiac action potential.

References : Yamashita T. et al.: J. Pharmacol Exp Ther., 274(1), 315-21, 1995; Desaphy J. F. et al.: J. Physiol., 554(Pt 2), 321-34, 2004; Kohli V. Indian Heart J. 65(2), 168-71, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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