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Flubendazole

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SI-6436

Flubendazole, >98% (HPLC)

CAS No. : [31430-15-6]

IUPAC Name : Methyl (6-(4-fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamate

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Chemical Properites
Mol. Formula :
C16H12FN3O3
Mol. Weight :
313.29
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Flubendazole disrupts microtubule dynamics by inhibiting tubulin polymerization, producing potent anthelmintic effects. It also triggers apoptosis in colorectal cancer cells via STAT3 inhibition and autophagy activation, while elevating p53 and reducing Cyclin B1 and p‑cdc2. These combined actions support its use in both antiparasitic and anticancer research.

References : Lin S. et al.: J. Exp. Clin. Cancer Res., 38(1), 293, 2019; Zhou X. et al.: Cell Death Discov., 4, 18, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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