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Fluconazole β-D-glucuronide

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SL-3282

Fluconazole β-D-glucuronide, >98%

CAS No. : [136134-23-1]

Synonyms : Fluconazole glucuronide

IUPAC Name : (2R,3R,4R,5S,6R)-6-((2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

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Chemical Properites
Mol. Formula :
C19H20F2N6O7
Mol. Weight :
482.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fluconazole β-D-glucuronide is a metabolite of Fluconazole, which is a fungal lanosterol 14 alpha-demethylase inhibitor, which thereby prevents the formation of ergosterol, used in the treatment and prevention of superficial and systemic fungal infections.

References : Uppuluri P. et al.: Antimicrob Agents Chemother., 52(3), 1127-1132, 2008; Rogers T. E. et al.: Antimicrob Agents Chemother., 30(3), 418-422, 1986; Chin N. X. et al.: Antimicrob Agents Chemother., 41(4), 850-852, 1997; Larsen R. A. et al.: Antimicrob Agents Chemother., 40(9), 2178-2182, 1996.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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