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Flumazenil-d5

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SL-10626

Flumazenil-d5, >98%

CAS No. : [2700278-14-2]

Synonyms : Ro 15-1788-d5

IUPAC Name : Ethyl-d5 8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate

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Chemical Properites
Mol. Formula :
C15H9D5FN3O3
Mol. Weight :
308.32
Appearance :
Solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Flumazenil-d5 is a deuterium labelled version of Flumazenil. This can be used as an analytical labelled reference standard. Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

References : Hoffman E. J. et al.: Clin Pharm., (9)641-56, 699-701, 1993; Belzung C. et al.: Psychopharmacology (Berl) 148(1), 24-32, 2000; Fernandez-Guasti A. et al.: Eur J. Pharmacol., 281(1), 113-5, 1995; Loscher W. et al.: Br. J. Pharmacol., 113(4), 1349-57, 1994; Moy S. S. et al.: Psychopharmacology (Berl), 131(4), 354-60, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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