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Flumazenil EP impurity D

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Flumazenil EP impurity D, >98%

CAS No. : [78755-80-3]

IUPAC Name : 7-Fluoro-4-methyl-3,4-dihydro-1H-benzo[e][1,4]diazepine-2,5-dione

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Chemical Properites
Mol. Formula :
C10H9FN2O2
Mol. Weight :
208.19
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Flumazenil, which is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

References : Hoffman E. J. et al.: Clin Pharm., (9)641-56, 699-701, 1993; Belzung C. et al.: Psychopharmacology (Berl) 148(1), 24-32, 2000; Fernandez-Guasti A. et al.: Eur J. Pharmacol., 281(1), 113-5, 1995; Loscher W. et al.: Br. J. Pharmacol., 113(4), 1349-57, 1994; Moy S. S. et al.: Psychopharmacology (Berl), 131(4), 354-60, 1997.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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