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Fluoro-homoneplanocin A

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SI-4785

Fluoro-homoneplanocin A, >98% (HPLC)

CAS No. : [1373314-02-3]

IUPAC Name : (1S,2R,5S)-5-(6-Amino-9H-purin-9-yl)-4-fluoro-3-(2-hydroxyethyl)cyclopent-3-ene-1,2-diol

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Chemical Properites
Mol. Formula :
C12H14FN5O3
Mol. Weight :
295.27
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an analog of Neplanocin A, which is a potent inhibitor of S-adenosylhomocysteine (AdoHcy) hydrolase and of vaccinia virus multiplication in mouse L929 cells.

References : Borchardt R. T. et al.: J. Biol. Chem., 259(7), 4353-4358, 1984; Chandra G. et al.: J. Med. Chem., 58(12), 5108-5120, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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