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Fluphenazine sulphone

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Fluphenazine sulphone, >98%

CAS No. : [1476-79-5]

MDL No. : MFCD31543889

Synonyms : 4-[3-[5,5-Dioxido-2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol; Fluphenazine EP impurity B; Fluphenazine impurity B

IUPAC Name : 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol S,S-dioxide

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Chemical Properites
Mol. Formula :
C22H26F3N3O3S
Mol. Weight :
469.52
Appearance :
Light brown semi solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : Fluphenazine sulphone is an impurity of Fluphenazine (Fluphenazine EP impurity B), which is a phenothiazine-class D1DR and D2DR inhibitor; used to deliver Fluphenazine to biological systems in studies probing the effects and metabolic fates of this commonly used dopamine antagonist.

References : Trzeciak H. I. et al.: Arzneimittelforschung 26(9), 1697-700, 1976; Whelpton R. Curry S. H. J. Pharm. Pharmacol., 28(12), 869-873, 1976; Javaid J. I. et al.: J. Chromatogr Sci.,19(9), 439-443, 1981.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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