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Fluticasone EP impurity F

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Fluticasone EP impurity F, >98%

CAS No. : [1219174-94-3]

Synonyms : 11-Oxofluticasone propionate

IUPAC Name : (6S,8S,9R,10S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-10,13,16-trimethyl-3,11-dioxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate

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Chemical Properites
Mol. Formula :
C25H29F3O5S
Mol. Weight :
498.56
Appearance :
White to Off-white solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fluticasone propionate (Fluticasone EP impurity F), which is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.

References : Baouz S. et al.: Int Immunol., 17(11), 1473-1481, 2005; Cazes E. et al.: J. Immunol., 167(9), 5329-5337, 2001; Powell N. et al.: Clin Exp Allergy 31(1), 69-76, 2001; Giguere S. et al.: Vet Immunol Immunopathol., 85(3-4), 147-158, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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