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Fluticasone EP impurity G

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SL-5564

Fluticasone EP impurity G, >96%

CAS No. : [220589-37-7]

Synonyms : 6α,9-Difluoro-17-[[(fluoromethyl)sulphanyl]carbonyl]-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-dien-17α-yl 6α,9-difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carboxylate; Fluticasone USP related compound E; Fluticasone dimer impurity

IUPAC Name : (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-Difluoro-17-(((fluoromethyl)thio)carbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthrene-17-carboxylate

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5MGRequest A Quote
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Chemical Properites
Mol. Formula :
C43H51F5O8S
Mol. Weight :
822.93
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fluticasone propionate (Fluticasone EP impurity G), which is a synthetic glucocorticoid, used to treat non-allergic and allergic rhinitis.

References : Baouz S. et al.: Int Immunol., 17(11), 1473-1481, 2005; Cazes E. et al.: J. Immunol., 167(9), 5329-5337, 2001; Powell N. et al.: Clin Exp Allergy 31(1), 69-76, 2001; Giguere S. et al.: Vet Immunol Immunopathol., 85(3-4), 147-158, 2002.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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