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FN-1501

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SI-7784

FN-1501, >98% (HPLC)

CAS No. : [1429515-59-2]

Synonyms : LT-171-861

IUPAC Name : 4-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrazole-3-carboxamide

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Chemical Properites
Mol. Formula :
C22H25N9O
Mol. Weight :
431.5
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : FN‑1501 potently inhibits CDK2, CDK4, CDK6, and FLT3 at sub‑nanomolar to low‑nanomolar concentrations (IC50= 0.28–2.47 nM). Its combined CDK and FLT3 blockade contributes to its strong anticancer activity across multiple tumor models.

References : Wang Y. et al.: J. Med. Chem., 61(4), 1499-1518, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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