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Folinic acid-d4

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Folinic acid-d4, >98%

CAS No. : [461426-40-4]

Synonyms : Leucovorin-d4

IUPAC Name : (4-(((2-Amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl)methyl)amino)benzoyl-d4)-L-glutamic acid

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Chemical Properites
Mol. Formula :
C20H19D4N7O7
Mol. Weight :
477.47
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium-labelled version of Folinic acid, which is a type of biological Folic acid that is commonly administered alongside Methotrexate as a rescue agent to help reduce the toxicity associated with MTX.

References : Keshava C. et al.: Mutat Res., 397(2), 221-8, 1998; Iqbal M. P. et al.: Acta Paediatr., 92(12), 1438-44, 2003.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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