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Fosfomycin EP impurity C

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Fosfomycin EP impurity C, >98%

CAS No. : [23001-39-0]

Synonyms : 1,3-Propanediol 2-amino-2-(hydroxymethyl)mono(dihydrogen phosphate) (ester) (8CI); 2-Amino-3-hydrox-2-(hydroxymethyl)propyl dihydrogen phosphate tris-phosphate; [2-Amino-3-hydroxy-2-(hydroxymethyl)propoxy]phosphonic acid

IUPAC Name : 2-Amino-3-hydroxy-2-(hydroxymethyl)propyl dihydrogen phosphate

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Chemical Properites
Mol. Formula :
C4H12NO6P
Mol. Weight :
201.11
Appearance :
Off-white solid (hygroscopic)
Melting Point :
Not available
Solubility :
H2O
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Fosfomycin sodium, which is a broad-spectrum antibiotic that crosses the blood-brain barrier and irreversibly inhibits early cell wall synthesis. Fosfomycin sodium is active in vivo and in vitro against many bacteria, including MDR, XDR, and PDR strains.

References : Falagas M. E. et al.: Clin Microbiol Rev., 29(2), 321-47, 2016; Dijkmans A. C. et al.: Antibiotics (Basel). 6(4), 24, 2017; Inouye S. et al.: J. Pharmacobiodyn, 5(9), 659-69, 1982; Inouye S. et al.: J. Pharmacobiodyn, 5(12), 941-50, 1982.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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