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Fosnetupitant

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SL-8569

Fosnetupitant, >98%

CAS No. : [1703748-89-3]

IUPAC Name : (4-(5-(2-(3,5-Bis(trifluoromethyl)phenyl)-N,2-dimethylpropanamido)-4-(o-tolyl)pyridin-2-yl)-1-methylpiperazin-1-ium-1-yl)methyl hydrogen phosphate

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Chemical Properites
Mol. Formula :
C31H35F6N4O5P
Mol. Weight :
688.61
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Fosnetupitant is a methylene phosphate proagent of Netupitant, which is a highly potent and selective, orally active neurokinin-1 receptor (NK-1) antagonist. This is used to prevent nausea and vomiting that is caused by cancer medicines.

References : Ruzza C. et al.: Peptides 69, 26-32, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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