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Fosravuconazole L-lysine ethanolate

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SI-5219

Fosravuconazole L-lysine ethanolate, >98% (HPLC)

CAS No. : [914361-45-8]

Synonyms : BMS-379224 L-lysine ethanolate; E-1224 L-lysine ethanolate

IUPAC Name : L-Lysine-(((2R,3R)-3-(4-(4-cyanophenyl)thiazol-2-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-yl)oxy)methyl dihydrogen phosphate--ethanol (1/1/1)

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Chemical Properites
Mol. Formula :
C23H20F2N5O5PS . C6H14N2O2 . CH3CH2OH
Mol. Weight :
739.73
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fosravuconazole L-lysine ethanolate is a prodrug of Ravuconazole, which is an orally active broad spectrum antifungal agent. Fosravuconazole L-lysine ethanolate can be used for candidiasis, onychomycosis and parasitemia research.

References : Watanabe S. et al.: J. Dermatol., 45(10), 1151-1159, 2018; Hata K. et al.: Parasitol Int., 81, 102278, 2020; Lívia de Figueiredo Diniz et al. Antimicrob Agents Chemother., 62(6), e00401-18, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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