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Fostamatinib-d9

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SI-5242

Fostamatinib-d9, >98% (HPLC)

Isotopic Purity : 98 atom % D

CAS No. : [1260832-60-7]

Synonyms : R788-d9

IUPAC Name : (6-((5-Fluoro-2-((3,4,5-tris(methoxy-d3)phenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2,3-dihydro-4H-pyrido[3,2-b][1,4]oxazin-4-yl)methyl dihydrogen phosphate

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H17D9FN6O9P
Mol. Weight :
589.52
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Fostamatinib-d9 is a deuterium labelled version an analog of Fostamatinib, which is an oral prodrug of the active compound Tamatinib. Tamatinib is an orally available and competitive Syk/FLT3 inhibitor. Tamatinib is a potential drug for treatment of the inflammation associated with and causing bronchial asthma resulting from allergen-induced airway hyperresponsiveness (AHR).

References : McAdoo P. S. et al.: Drugs Future 36(4), 273,2011; Sylvia Braselmann S. et al.: J. Pharmacol Exp Ther., 319(3), 998-1008, 2006; Hoon-Suk Cha et al.: J. Pharmacol Exp Ther., 317(2), 571-578, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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