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FOY-251-d4 benzyl ester

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SL-6062

FOY-251-d4 benzyl ester, >98% (CP)

Isotopic Purity : 98 atom % D

Related CAS No. : [744150-79-6] of the unlabelled compound

IUPAC Name : 4-(2-(Benzyloxy)-2-oxoethyl)phenyl 4-guanidinobenzoate-d4

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Chemical Properites
Mol. Formula :
C23H17D4N3O4
Mol. Weight :
407.46
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : FOY-251-d4 benzyl ester is a deuterium labelled version an analog of Camostat, which is a trypsin-like protease inhibitor. Camostat is approved in Japan for the treatment of chronic pancreatitis and postoperative reflux esophagitis.

References : Coote K. et al.: J. Pharmacol Exp Ther., 329(2), 764-774, 2009; Okuno M. et al.: Gastroenterology 120(7), 1784-1800, 2001; Yamamoto A. et al.: Pharm Res., 11(10), 1496-1500, 1994; Gibo J. et al.: Lab Invest., 85(1), 75-89, 2005; Su S. B. et al.: Pancreas 23(2), 134-140, 2001.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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