Fragment (1-4)-Linaclotide

SL-12142

Fragment (1-4)-Linaclotide, >95%

Synonyms : Linaclotide inactive degradation product-1; H-Cys-Cys-Glu-Tyr-OH

IUPAC Name : (S)-4-((R)-2-((R)-2-Amino-3-mercaptopropanamido)-3-mercapto propanamido)-5-(((S)-1-carboxy-2-(4-hydroxyphenyl) ethyl)amino)-5-oxopentanoic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an impurity of Linaclotide, which is a potent and selective guanylate cyclase C agonist; developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation.

References : Bryant A. P. et al.: Life Sci., 86(19-20), 760-765, 2010; Love B. L. et al.: Am. J. Health Syst Pharm., 71(13), 1081-91, 2014.

Storage : Keep container tightly closed under nitrogen or argon and store at -20^oC for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.