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Furosemide EP impurity A

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SL-6889

Furosemide EP impurity A, >98%

CAS No. : [4818-59-1]

Synonyms : Isofurosemide

IUPAC Name : 2-Chloro-4-((furan-2-ylmethyl)amino)-5-sulfamoylbenzoic acid

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Chemical Properites
Mol. Formula :
C12H11ClN2O5S
Mol. Weight :
330.74
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Furosemide (Furosemide EP impurity A), which is a potent NKCC2 (Na-K-2Cl symporter) inhibitor, used in the treatment of congestive heart failure and edema.

References : Charak B. S. et al.: J. Antimicrob Chemother, 27(1), 95-104, 1991; Wiemer G. et al.: J. Pharmacol Exp Ther., 271(3), 1611-1615, 1994; .Gutschmidt K. U. et al.: Neuroscience 91(4), 1471-1481, 1999; Shiozaki A. et al.: J. Physiol Sci., 56(6), 401-406, 2006; Olsen S. C. et al.: Am J. Vet Res., 53(5), 742-747, 1992.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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