Galunisertib

SI-6477

Galunisertib, >98% (HPLC)

CAS No. : [700874-72-2]

Synonyms : LY-2157299

IUPAC Name : 4-(2-(6-Methylpyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline-6-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Galunisertib selectively inhibits TGF‑βRI kinase with an IC₅₀ of 56 nM, effectively suppressing TGF‑β–driven signaling cascades implicated in cancer, fibrosis, and immune modulation.

References : Cong L. et al.: . Arch. Pharm (Weinheim)., 347(9), 609-15, 2014; Serova M. et al.: Oncotarget., 6(25), 21614-27, 2015; Bueno L. et al.: Eur. J. Cancer., 44(1), 142-50, 2008; Herbertz S. et al.: Drug Des. Devel. Ther., 9, 4479-99, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.