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Gandotinib

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SI-6284

Gandotinib, >98% (HPLC)

CAS No. : [1229236-86-5]

Synonyms : LY-2784544

IUPAC Name : 3-(4-Chloro-2-fluorobenzyl)-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholinomethyl)imidazo[1,2-b]pyridazin-6-amine

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H25ClFN7O
Mol. Weight :
469.95
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Gandotinib selectively inhibits JAK2 with low‑nanomolar potency and additionally suppresses FLT3, FLT4, FGFR2, TYK2, and TRKB at nanomolar concentrations. This multi‑target activity makes it a valuable tool for probing JAK2‑dependent and FLT‑family signaling pathways.

References : Ma L. et al.: Blood Cancer J., 3, e109, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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