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CAS No. : [500579-04-4]
MDL No. : MFCD14635408
Synonyms : NSC 136476; GANT-61
IUPAC Name : 2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 50MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 100MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 250MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 500MG | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 1G | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C27H35N5 | Mol. Weight : 429.60 |
Appearance : White to Off-white solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway.
References : Mazumdar T. et al.: Cancer Res. 71 (3), 1092-1102, 2011; Fu J. et al. Cancer Lett., 330 (1), 22-32, 2013; Wickstrom M. et al.: Int. J. Cancer. 132 (7), 1516-24, 2013; Neelakantan D, et al. Nat Commun. 8, 15773, 2017.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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