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GANT61, >98%

CAS No. : [500579-04-4]

MDL No. : MFCD14635408

Synonyms : NSC 136476; GANT-61

IUPAC Name : 2,2′-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C27H35N5
Mol. Weight :
429.60
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway.

References : Mazumdar T. et al.: Cancer Res. 71 (3), 1092-1102, 2011; Fu J. et al. Cancer Lett., 330 (1), 22-32, 2013; Wickstrom M. et al.: Int. J. Cancer. 132 (7), 1516-24, 2013; Neelakantan D, et al. Nat Commun. 8, 15773, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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